Value of blood phenytoin estimation in management of childhood epilepsy.
نویسندگان
چکیده
From these results it seems that the presence of triangular hairs is on,! characteristic that contributes to a palpable coarseness of normal human hair. Triangular hairs are frequently seen in patients over the age of 2 years who have Hurler's syndrome or Sanfilippo syndrome. This finding is not claimed to have any diagnostic value. Should further studies reveal that triangular hairs are a universal feature of the Sanfilippo syndrome, the absence of this feature could help in exclusion of the diagnosis in retarded children with coarse features. Clinical recognition of this syndrome is not always easy, even in children 5 to 10 years of age.
منابع مشابه
مقایسهی سطح سرمی فنوباربیتال و فنیتوئین بین کودکان مبتلا به صرع پایدار و صرع پایدار مقاوم
Background & objective: Due to high kinetic variation of antiepileptic medications in children, judgment on the efficacy of intravenous phenytoin and phenobarbital in treatment of refractory status epilepsy, requires measurement of serum levels of the drugs. The aim of this study was determine and compare serum levels of phenytoin and phenobarbital, as the two major and common first- line drugs...
متن کاملAnticonvulsant drugs, growth, and development.
Height and stage of puberty of 67 children with epilepsy were measured before beginning treatment with anticonvulsant drugs and annually to a maximum five years' treatment. Blood concentrations of the drugs used (phenytoin, sodium valproate, carbamazepine, ethosuximide, and phenobarbitone) were monitored throughout. No significant deviation in growth patterns was detected.
متن کاملPhenytoin in Childhood Epilepsy
1. Summary statement of the proposal for inclusion, change or deletion Phenytoin base (as EpanutinR) is available as 50mg chewable tablets and an oral suspension of strength 30mg/5ml, and are proposed for addition to the Model List of Essential Medicines, for use in the management of epilepsy in children. It is at least as effective as carbamazepine, phenobarbitone and sodium valproate in the m...
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Introduction: Interaction between drugs represents a major clinical concern for health care professionals and their patients. Patients affected by both type 2 diabetes and epilepsy may be prescribed pioglitazone and an anti-epileptic drug such as phenytoin concurrently. The aim of this study was to consider the interaction of pioglitazone with phenytoin in an experimental model. According to t...
متن کاملN-octyl-modified magnetite NPs for optimization of solid phase extraction for trace analysis of phenytoin in real samples
objective: Phenytoin is an anti-seizure medication used to treat epilepsy, as well as to control arrhythmias (irregular heartbeat) and to treat migraine headaches and nerve pain. It is recommended to determine the amount of this drug in the blood to control the seizure and prevent its toxicity. In the present study, a sensitive and simple procedure based on the dispersive solid phase extraction...
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عنوان ژورنال:
- Archives of disease in childhood
دوره 46 247 شماره
صفحات -
تاریخ انتشار 1971